Bone densitometry versus bone histomorphometry in renal transplanted patients: a cross?sectional study

Bone loss leads to increase risk of fractures in renal transplantation. The aim this study was analyse the relationship between bone densitometry (DXA) findings, histomorphometry and bone-related molecules 1-year after We performed a cross-sectional de novo transplanted patients that agreed perform biopsy DXA examination 1 year All underwent laboratory evaluation, biopsy, cardiac CT 67 were included, 16 had normal examination, 18 classified as having osteoporosis by DXA. Correlations mineral density T-scores total femur femoral neck ones best correlated with volume assessed biopsy. sensitivity for diagnosis 47.0%, specificity 81.2%. positive predictive value 50.0%, negative (NPV) 80.0%. parameters also klotho sclerostin serum levels. In population, excluded presence osteoporosis, helping identifying would not benefit from therapy. Overall, well measured